Julia is the most popular girl in school. She's fit, attractive, cool and everyone wants to be like her. When she gets paired with the hot but geeky Josh on a field trip to a research facility the two get into more trouble than either of them can handle. They get separated from their classmates and end up in a restricted area where experiments are conducted. Unfortunately for them, they become the experiment and a freak accident causes them to switch bodies! Before they can switch back they're going to have to take a crash course in anatomy.