Washes Away Undesirable Particles*100% PureVegetarian ProductD-Mannose is a simple sugar that occurs naturally in some plants, including cranberries. Although small amounts of D-Mannose are metabolized by the human body, much of it is rapidly excreted in the urine. In the bladder. ?Because insubstantial amounts of D-Mannose are used by the body, it does not interfere with blood sugar regulation.